BAVgenetics is a partnership between Investigators at Brigham and Women’s Hospital, Massachusetts General Hospital and the Harvard-Partners Center for Genetics and Genomics, dedicated to discovering the genetic causes of bicuspid aortic valve disease and associated aortic disease.
As you may know, the aortic valve is the valve that blood passes through from the main pumping chamber of the heart. Normally, the aortic valve has three leaflets, but in about 1% of the population, the valve has two leaflets, as seen in the picture above.
The Investigators at BAVgenetics are dedicated to discovering the mechanisms of bicuspid aortic valve disease and why individual genetics seem to play such an important role in generation of this disease.
If you have, or have had, a bicuspid aortic valve, we seek your help in this effort by volunteering to donate DNA and details of your disease to the Investigators, so that this disease can be better understood and therapies for it can be developed.
If you want to read more about bicuspid aortic valve disease, we suggest exploring these web sites:
There is an Association for patients and families of those with bicuspid aortic valve disease. Their very informative web site is at: